Welcome to Entry Card of Peptide


This page gives details of CPPsite entry with ID 2312
Primary information
CPPsite ID2312
PEPTIDE SEQUENCERQIKIWFQNRRMKWKK
PEPTIDE NAMEPenetratin
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic and amphipathic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLower uptake efficiency
INVITRO/INVIVOIn vitro and in vivo
CELL LINECT26 mouse colon cancer cells, HeLa and Hep3B cells
In VIVO MODELMale Balb/c mice
CARGOPeptide (Mitochondrial Target Domain of NOXA)
PMID24416126
PATENTUnknown
LENGTH16
Secondary StructureCCCSSHHHHHHSSSCC
SMILES[NH3][C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCC[NH3])CCCC[NH3])Cc1c[nH]c2c1cccc2)CCCC[NH3])CCSC)CCCNC(=[NH2])N)CCCNC(=[NH2])N)CC(=O)N)CCC(=O)N)Cc1ccccc1)Cc1c[nH]c2c1cccc2)[C@H](CC)C)CCCC[NH3])[C@H](CC)C)CCC(=O)N)CCCNC(=[NH2])N
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (Experimentally determined structure from PDB)