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This page gives details of CPPsite entry with ID 2303
Primary information
CPPsite ID2303
PEPTIDE SEQUENCECGGKDCERRFSRSDQLKRHQRRHTGVKPFQ
PEPTIDE NAMEb-WT1-pTj
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONBiotinylation
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigher uptake efficency
INVITRO/INVIVOIn vitro and in vivo
CELL LINEA2058 human melanoma cells, B16F10-Nex2 syngeneic murine melanoma, HFF and MEF cells-- A2058 and SK-MEL-28, MCF-7 and MDA-MB231, OVCAR-3 and HL-61
In VIVO MODELSix-to-eight week-old, C57BL / syngeneic mice
CARGOBiotin
PMID24490140
PATENTUnknown
LENGTH30
Secondary StructureCCSSCSCCSSSSGGGGGGCTTSSSCSCCCC
SMILESN[C@@H](CS)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H]
Tertiary Structure
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  (PEPstrMOD)