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This page gives details of CPPsite entry with ID 2260
Primary information
CPPsite ID2260
PEPTIDE SEQUENCEISFDELLDYYGESGS
PEPTIDE NAMENYAD-41
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
N-TERMINAL MODIFICATIONAcetylation
C-TERMINAL MODIFICATIONFree
CHEMICAL MODIFICATIONS5 [(S)-2-(4′-pentenyl)alanine] and R8 [(R)-2-(7′-octenyl)alanine] indicate stapling sites in the peptide sequence.
INVITRO/INVIVOIn vitro
CELL LINEMT-2 cells, TZM-bl cells (a HeLa cell line derivative),HEK 293T cells, primary human cells, Jurkat
CARGOFluorophore (FAM)
PMID24237936
PATENTUnknown
LENGTH15
Secondary StructureCCSGGGTTTTSCSCC
SMILESN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C=O
Tertiary Structure
(Technique)
View in Jmol  OR Download Structure
 (PEPstrMOD)