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This page gives details of CPPsite entry with ID 2242
Primary information
CPPsite ID2242
PEPTIDE SEQUENCEGRKKRRQRRRPPQY
PEPTIDE NAMETat-Dex
CHIRALITYL
LINEAR/CYCLICCyclic
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONDexamethasone
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHEK293, HeLa, MCF-7, NIH 3T3, A549, Jurkat, H1650, and H1299 cells
CARGODexamethasone
PMID24896852
PATENTUnknown
LENGTH14
Secondary StructureCCTTSCCCCCCSCC
SMILESNCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C=O
Tertiary Structure
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  (PEPstrMOD)