Welcome to Entry Card of Peptide


This page gives details of CPPsite entry with ID 2236
Primary information
CPPsite ID2236
PEPTIDE SEQUENCECLLYWFRRRHRHHRRRHRRC
PEPTIDE NAMEMgpe-10
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYPrimary Amphipathic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
CHEMICAL MODIFICATIONAddition of cysteine in Mgpe4 sequence makes Mgpe10
UPTAKE EFFICIENCYLess efficient peptide for DNA uptake (comparison to Mgpe-4)
INVITRO/INVIVOIn vitro
CELL LINEA549, MCF-7, HeLa, HEK, T47D, B16, MDA-MB 231, B35 and U 87, CHO-K1, H-1299, JURKAT and RAW
CARGONucleic acid (Plasmid DNA)
PMID24816284
PATENTUnknown
LENGTH20
Secondary StructureCCSSHHHHTTCCSSSCCSCC
SMILESN[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CS)C
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)