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This page gives details of CPPsite entry with ID 2216
Primary information
CPPsite ID2216
PEPTIDE SEQUENCERRRRRRRRC
PEPTIDE NAMER8
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigher than RIPL R8
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINELNCaP, SK-OV-3, and MCF-7 as Hpn-expressing cells, DU-145, PC-3, and HaCaT as Hpn-non-expressing cells
CARGOFluorophore (FITC)
PMID24704199
PATENTUnknown
LENGTH9
Secondary StructureCCCSCCCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CS)CO
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)