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This page gives details of CPPsite entry with ID 2166
Primary information
CPPsite ID2166
PEPTIDE SEQUENCEPKKKRKVWKLLQQFFGLM
PEPTIDE NAMEFITC-NS
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONNucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONSpacer 6-aminohexanoic acid (Ahx)
UPTAKE EFFICIENCYHigher Uptake
PROPOSED UPTAKE MECHANISMCaspase-independent pathway
INVITRO/INVIVOIn vitro
CELL LINEHeLa
CARGOFluorophore (FITC)
PMID24958615
PATENTUnknown
LENGTH18
Secondary StructureCGGGGGGCSGGGCTTTTC
SMILESN1CCC[C@H]1C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C=O
Tertiary Structure
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  (PEPstrMOD)