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This page gives details of CPPsite entry with ID 2160 |
| Primary information | |
|---|---|
| CPPsite ID | 2160 |
| PEPTIDE SEQUENCE | RRRRRRRR |
| PEPTIDE NAME | R8 |
| CHIRALITY | L |
| LINEAR/CYCLIC | Linear |
| SOURCE | Synthetic |
| CATEGORY | Cationic |
| SUB CELLULAR LOCALIZATION | Cytoplasm |
| N-TERMINAL MODIFICATION | Acetylation |
| C-TERMINAL MODIFICATION | Amidation |
| UPTAKE EFFICIENCY | More than 50% of cells had anti-miRNA/R8 complexes and 68% of anti-miRNA escapes the endosome/lysosome. |
| PROPOSED UPTAKE MECHANISM | Endocytosis |
| INVITRO/INVIVO | In vitro |
| CELL LINE | Glioblastoma U251 |
| CARGO | Nucleic acid (siRNA and miRNA) |
| PMID | 24969623 |
| PATENT | Unknown |
| LENGTH | 8 |
| Secondary Structure | CCCCCCCC |
| SMILES | CC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N |
| Tertiary Structure (Technique) | View in Jmol OR Download Structure (PEPstrMOD) |