This page gives details of CPPsite entry with ID 2125 |
Primary information | |
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CPPsite ID | 2125 |
PEPTIDE SEQUENCE | CHHRRRRHHC |
PEPTIDE NAME | CH2 R4 H2 C |
CHIRALITY | L |
LINEAR/CYCLIC | Cyclic |
SOURCE | Synthetic |
SUB CELLULAR LOCALIZATION | Cytoplasm |
N-TERMINAL MODIFICATION | Stearylation |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | The cellular uptake ability of the carrier/FAM-siRNA complexes with fetal bovine serum was significantly higher than that of naked FAM-siRNA |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | S-180 sarcoma cells |
In VIVO MODEL | ICR male mice |
CARGO | Nucleic aciud (siRNA) |
PMID | 23911914 |
PATENT | Unknown |
LENGTH | 10 |
Secondary Structure | CCCGGGSCCC |
SMILES | N[C@@H](CS)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CS)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |