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This page gives details of CPPsite entry with ID 2125
Primary information
CPPsite ID2125
PEPTIDE SEQUENCECHHRRRRHHC
PEPTIDE NAMECH2 R4 H2 C
CHIRALITYL
LINEAR/CYCLICCyclic
SOURCESynthetic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONStearylation
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYThe cellular uptake ability of the carrier/FAM-siRNA complexes with fetal bovine serum was significantly higher than that of naked FAM-siRNA
INVITRO/INVIVOIn vitro and in vivo
CELL LINES-180 sarcoma cells
In VIVO MODELICR male mice
CARGONucleic aciud (siRNA)
PMID23911914
PATENTUnknown
LENGTH10
Secondary StructureCCCGGGSCCC
SMILESN[C@@H](CS)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CS)C=O
Tertiary Structure
(Technique)
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