This page gives details of CPPsite entry with ID 2070 |
Primary information | |
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CPPsite ID | 2070 |
PEPTIDE SEQUENCE | EEEEEEEEEE-PLGLAG-VSRRRRRRGGRRRR |
PEPTIDE NAME | ALWMP |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Free |
CHEMICAL MODIFICATION | Linker (PLGLAG) |
PROPOSED UPTAKE MECHANISM | Clathrin-mediated and cytoskeleton-dependent endocytosis as well as energy independent internalization |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | HT-1080 and brain capillary endothelial cell bEnd.3 cell line |
In VIVO MODEL | Adult male BALB/c nude mice and male SpragueDawley rats |
CARGO | Nanoparticles and Fluoriophore (coumarin-6) |
PMID | 23350619 |
PATENT | Unknown |
LENGTH | 24 |
Secondary Structure | CHHHHHHHHTGGGSHHHHHHHHHHHHHHHC |
SMILES | N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C=O)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CO)C(C)C)C)CC(C)C)CC(C)C)CCC)CCC(=O)O)CCC(=O)O)CCC( |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (Homology based) |