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This page gives details of CPPsite entry with ID 2070
Primary information
CPPsite ID2070
PEPTIDE SEQUENCEEEEEEEEEEE-PLGLAG-VSRRRRRRGGRRRR
PEPTIDE NAMEALWMP
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
CHEMICAL MODIFICATIONLinker (PLGLAG)
PROPOSED UPTAKE MECHANISMClathrin-mediated and cytoskeleton-dependent endocytosis as well as energy independent internalization
INVITRO/INVIVOIn vitro and in vivo
CELL LINEHT-1080 and brain capillary endothelial cell bEnd.3 cell line
In VIVO MODELAdult male BALB/c nude mice and male SpragueDawley rats
CARGONanoparticles and Fluoriophore (coumarin-6)
PMID23350619
PATENTUnknown
LENGTH24
Secondary StructureCHHHHHHHHTGGGSHHHHHHHHHHHHHHHC
SMILESN[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C=O)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CO)C(C)C)C)CC(C)C)CC(C)C)CCC)CCC(=O)O)CCC(=O)O)CCC(
Tertiary Structure
(Technique)
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 (Homology based)