This page gives details of CPPsite entry with ID 2009 |
Primary information | |
---|---|
CPPsite ID | 2009 |
PEPTIDE SEQUENCE | WRWKKKKA |
PEPTIDE NAME | cyclic [W(RW)4] |
CHIRALITY | L |
LINEAR/CYCLIC | Cyclic |
SOURCE | Synthetic |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Nucleus |
CHEMICAL MODIFICATION | Drug conjugated with peptide through linker |
UPTAKE EFFICIENCY | Higher than (RW)4 |
INVITRO/INVIVO | In vitro |
CELL LINE | MDA-MB-468, HCT-116, CCRF-CEM, and SK-OV-3 |
CARGO | Small molecule drug (Doxorubicin) |
PMID | 23301519 |
PATENT | Unknown |
LENGTH | 8 |
Secondary Structure | CCCCCSCC |
SMILES | N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |