This page gives details of CPPsite entry with ID 1842 |
Primary information | |
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CPPsite ID | 1842 |
PEPTIDE SEQUENCE | GRKKRRQRRRPP |
PEPTIDE NAME | Tat (48-59) |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Punctate distribution (vesicles) |
N-TERMINAL MODIFICATION | Conjugation with fluorescein |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | Unknown |
PROPOSED UPTAKE MECHANISM | Energy dependent endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | HeLa and CHO K1 and Jurkat |
CARGO | Fluorophore (fluorescein) |
PMID | 12411431 |
PATENT | Unknown |
LENGTH | 12 |
Secondary Structure | CCCSCCCCCCCC |
SMILES | NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |