This page gives details of CPPsite entry with ID 1810 |
Primary information | |
---|---|
CPPsite ID | 1810 |
PEPTIDE SEQUENCE | RRRRRRRRRRRTYADFIASGRTGRRNAI |
PEPTIDE NAME | R11-PKI |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Chimeric |
CATEGORY | Unknown |
SUB CELLULAR LOCALIZATION | Unknown |
N-TERMINAL MODIFICATION | Conjugation with rhodamine B |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | Greater than pAntp-PKI, Tat-PKI but equal to trans |
PROPOSED UPTAKE MECHANISM | Unknown |
INVITRO/INVIVO | In vitro |
CELL LINE | CHO K1, HeLa, A549 cells |
CARGO | Fluorophore (rhodamine) |
PMID | 15937518 |
PATENT | Unknown |
LENGTH | 28 |
Secondary Structure | CGGGGGGCCCCCHHHHHHSSSCGGGSCC |
SMILES | N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2] |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |