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This page gives details of CPPsite entry with ID 1806
Primary information
CPPsite ID1806
PEPTIDE SEQUENCEGRKKRRQRRRPPQTYADFIASGRTGRRNAI
PEPTIDE NAMETat-PKI
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYUnknown
SUB CELLULAR LOCALIZATIONUnknown
N-TERMINAL MODIFICATIONConjugation with rhodamine B
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLess than polyarginine-PKI, Antp-PKI and Transport
PROPOSED UPTAKE MECHANISMLipid raft-dependent but clathrin-independent endocytic process
INVITRO/INVIVOIn vitro
CELL LINECHO K1, HeLa, A549 cells
CARGOFluorophore (rhodamine)
PMID15937518
PATENTUnknown
LENGTH30
Secondary StructureCBTTBCCCCCCSSSSSTHHHHCCSSSCCCC
SMILESNCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C
Tertiary Structure
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