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This page gives details of CPPsite entry with ID 1805
Primary information
CPPsite ID1805
PEPTIDE SEQUENCEGRKKRRQRRRPPQ
PEPTIDE NAMETat
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONUnknown
N-TERMINAL MODIFICATIONConjugation with rhodamine B
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLess than polyarginine and pAntp but equal to tran
PROPOSED UPTAKE MECHANISMLipid raft-dependent but clathrin-independent endocytic process
INVITRO/INVIVOIn vitro
CELL LINECHO K1, HeLa, A549 cells
CARGOFluorophore (rhodamine)
PMID15937518
PATENTUnknown
LENGTH13
Secondary StructureCCTTSCCSSCSCC
SMILESNCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C=O
Tertiary Structure
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  (PEPstrMOD)