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This page gives details of CPPsite entry with ID 1555
Primary information
CPPsite ID1555
PEPTIDE SEQUENCEKRVSRNKSEKKRR
PEPTIDE NAMEhClock-(35-47)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus, but mainly in the nucleus with a nucleolar accumula
N-TERMINAL MODIFICATIONConjugation with FITC
UPTAKE EFFICIENCYSimilar to Tat (48-60)
PROPOSED UPTAKE MECHANISMNon-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEECV-304 and the primary neuroglial cells
CARGOFluorophore (FITC)
PMID15346201
PATENTUnknown
LENGTH13
Secondary StructureCCCCCCGGGGGCC
SMILESN[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)