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This page gives details of CPPsite entry with ID 1500
Primary information
CPPsite ID1500
PEPTIDE SEQUENCEGRRRRRRRRRPPQ
PEPTIDE NAMER9-TAT
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with fluorescein at cysteine
UPTAKE EFFICIENCYHigh comparable to Tat(48-60)
PROPOSED UPTAKE MECHANISMProbably non-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINERAW 264.7 cells
CARGOFluorophore (fluorescein)
PMID11084031
PATENTUnknown
LENGTH13
Secondary StructureCCCCCCCTTSSCC
SMILESNCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)CO
Tertiary Structure
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  (PEPstrMOD)