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This page gives details of CPPsite entry with ID 1490
Primary information
CPPsite ID1490
PEPTIDE SEQUENCERQIKIWFQNRRMKWKK
PEPTIDE NAMEPenetratin {pAntp-(43-58)}
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus
N-TERMINAL MODIFICATIONBiotinylation
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYUnknown
PROPOSED UPTAKE MECHANISMNon-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHuman bowes melanoma cells
CARGOBiotin
PMID11716681
PATENTUnknown
LENGTH16
Secondary StructureCCCSSHHHHHHSSSCC
SMILES[NH3][C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCC[NH3])CCCC[NH3])Cc1c[nH]c2c1cccc2)CCCC[NH3])CCSC)CCCNC(=[NH2])N)CCCNC(=[NH2])N)CC(=O)N)CCC(=O)N)Cc1ccccc1)Cc1c[nH]c2c1cccc2)[C@H](CC)C)CCCC[NH3])[C@H](CC)C)CCC(=O)N)CCCNC(=[NH2])N
Tertiary Structure
(Technique)
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 (Experimentally determined structure from PDB)