This page gives details of CPPsite entry with ID 1489 |
Primary information | |
---|---|
CPPsite ID | 1489 |
PEPTIDE SEQUENCE | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTESC |
PEPTIDE NAME | LL-37 |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Antimicrobial |
SUB CELLULAR LOCALIZATION | Nucleus |
C-TERMINAL MODIFICATION | Amidation |
UPTAKE EFFICIENCY | Unknown |
PROPOSED UPTAKE MECHANISM | Membrane raft endocytosis and proteoglycan-dependent endocytic process |
INVITRO/INVIVO | In vitro |
CELL LINE | COS-7, HFL-1 and CHO-K1 cells |
CARGO | Nucleic acid |
PMID | 14963039 |
PATENT | Unknown |
LENGTH | 38 |
Secondary Structure | CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC |
SMILES | N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C=O)CS)CO)CCC(=O)O)[C@H](O)C)CCCNC(=N)N)CCC)C(C)C)CC(C)C)CC |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (Homology based) |