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This page gives details of CPPsite entry with ID 1484
Primary information
CPPsite ID1484
PEPTIDE SEQUENCERGGRLAYLRRRWAVLGR
PEPTIDE NAMESynB5
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYAntimicrobial
SUB CELLULAR LOCALIZATIONEndocytic vesicles
N-TERMINAL MODIFICATIONConjugation with NBD and TAMRA
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLower than pAntp-(43–58)
PROPOSED UPTAKE MECHANISMAdsorptive-mediated endocytic process
INVITRO/INVIVOIn vitro
CELL LINEK562 cells
CARGOFluorophore (NBD and TAMRA)
PMID12783857
PATENTUnknown
LENGTH17
Secondary StructureCCSCCHHHHHTSSTTCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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