This page gives details of CPPsite entry with ID 1464 |
Primary information | |
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CPPsite ID | 1464 |
PEPTIDE SEQUENCE | GYGRKKRRQRRRG |
PEPTIDE NAME | Tat (47-57) |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Punctuated cytoplasmic (vesicles) as well as extracellular staining |
N-TERMINAL MODIFICATION | Carries an extra glycine and Conjugation with fluores |
C-TERMINAL MODIFICATION | Carries an extra glycine |
UPTAKE EFFICIENCY | Unknown |
PROPOSED UPTAKE MECHANISM | Condition dependent (not determined in this paper) |
INVITRO/INVIVO | In vitro |
CELL LINE | Calu-3 cells |
CARGO | Fluorophore (fluorescein) |
PMID | 15290867 |
PATENT | Unknown |
LENGTH | 13 |
Secondary Structure | CCCCGGGGTTCCC |
SMILES | NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |