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This page gives details of CPPsite entry with ID 1453
Primary information
CPPsite ID1453
PEPTIDE SEQUENCEGKKKKRKREKL
PEPTIDE NAMETCF1-ALPHA
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONUnknown
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCY50% relative to Oct-6
PROPOSED UPTAKE MECHANISMEnergy independent, non-receptor-mediated process
INVITRO/INVIVOIn vitro
CELL LINEMCF-7
CARGOFluorophore (fluorescein)
PMID12204694
PATENTUnknown
LENGTH11
Secondary StructureCHHHHHHHCCC
SMILESNCC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)