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This page gives details of CPPsite entry with ID 1450
Primary information
CPPsite ID1450
PEPTIDE SEQUENCEVQRKRQKLMP
PEPTIDE NAMENF-kB
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus, nucleolus
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYLower than Oct-6
PROPOSED UPTAKE MECHANISMEnergy dependent endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEMCF-7
CARGOFluorophore (fluorescein)
PMID12204694
PATENTUnknown
LENGTH10
Secondary StructureCHHHHTSCCC
SMILESN[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C=O
Tertiary Structure
(Technique)
View in Jmol  OR Download Structure
 (PEPstrMOD)