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This page gives details of CPPsite entry with ID 1446
Primary information
CPPsite ID1446
PEPTIDE SEQUENCEYYYAAGRKRKKRT
PEPTIDE NAMETyr-Oct-6
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEChimeric
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with FITC
UPTAKE EFFICIENCYLow
PROPOSED UPTAKE MECHANISMProbably energy dependent pathway
INVITRO/INVIVOIn vitro
CELL LINEDU-145 and LNCaP
CARGOFluorophore (FITC)
PMID21029412
PATENTUS 20100137187
LENGTH13
Secondary StructureCCCTTTSCCCCCC
SMILESN[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)O)C=O
Tertiary Structure
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  (PEPstrMOD)