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This page gives details of CPPsite entry with ID 1424
Primary information
CPPsite ID1424
PEPTIDE SEQUENCEGALFLGFLGAAGSTMGAWSQPKSKRKV
PEPTIDE NAMEMPG Mutant
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEChimeric
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONNucleus
N-TERMINAL MODIFICATIONAcetylation
C-TERMINAL MODIFICATIONCysteamide group
UPTAKE EFFICIENCYLower than wilde type MPG
PROPOSED UPTAKE MECHANISMNon-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHS-68, Cos-7 and HeLa
CARGOFluorophore (fluorescein)
PMID12771197
PATENTUnknown
LENGTH27
Secondary StructureCCCSSGGGGTTTTTCSTTTSSSCSCCC
SMILESNCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C(C)C)C=O
Tertiary Structure
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  (PEPstrMOD)