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This page gives details of CPPsite entry with ID 1401
Primary information
CPPsite ID1401
PEPTIDE SEQUENCEMDAQTRRRERRAEKQAQWKAANGC
PEPTIDE NAMELAMBDA N (1-22)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with fluorescein by C-terminal Gly Cys amide
UPTAKE EFFICIENCYLess relative to Tat-(48–60) peptide
PROPOSED UPTAKE MECHANISMNon-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINERAW 264.7
CARGOFluorophore (fluorescein)
PMID11084031
PATENTUnknown
LENGTH24
Secondary StructureCCTTTHHHHHHHHHHHTHHHHTCC
SMILESN[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)N[C@@H]
Tertiary Structure
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  (PEPstrMOD)