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This page gives details of CPPsite entry with ID 1381
Primary information
CPPsite ID1381
PEPTIDE SEQUENCEMVRRFLVTLRIRRACGPPRVRV
PEPTIDE NAMEARF(1-22)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYUnknown
SUB CELLULAR LOCALIZATIONPunctual/vesicular distribution (vesicles)
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigh, comparable to that of TP10
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEMCF-7 and MDA MB 231
CARGOFluorophore (fluorescein)
PMID17984975
PATENTUnknown
LENGTH22
Secondary StructureCGGGCCCSSCCTTSCSSSSSCC
SMILESN[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](C(C)C)C=O
Tertiary Structure
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  (PEPstrMOD)