This page gives details of CPPsite entry with ID 1309 |
Primary information | |
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CPPsite ID | 1309 |
PEPTIDE SEQUENCE | LLIILRRRIRKQaHAHSK |
PEPTIDE NAME | pVEC mutant |
CHIRALITY | Mix |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Probably Amphipathic |
SUB CELLULAR LOCALIZATION | Prabably cytoplasm and nucleus |
N-TERMINAL MODIFICATION | Conjugation with fluorescein |
C-TERMINAL MODIFICATION | Amidation |
UPTAKE EFFICIENCY | Comparable to pVEC |
PROPOSED UPTAKE MECHANISM | Probably receptor independent endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | Human bowes melanoma cells |
CARGO | Fluorophore (fluorescein) |
PMID | 16808894 |
PATENT | Unknown |
LENGTH | 18 |
Secondary Structure | CCCSSGGGHHHHTTTTCC |
SMILES | N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCC[NH3])CO |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |