This page gives details of CPPsite entry with ID 1181 |
Primary information | |
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CPPsite ID | 1181 |
PEPTIDE SEQUENCE | KCGCRWRWKCGCKK |
PEPTIDE NAME | Crot (27-39) derevative |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cystein rich |
SUB CELLULAR LOCALIZATION | Probably Cytosol |
N-TERMINAL MODIFICATION | Conjugation with K-FITC |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | High (75% of CyLoP1) |
PROPOSED UPTAKE MECHANISM | Probably Receptor mediated endocytic process |
INVITRO/INVIVO | In vitro |
CELL LINE | NIH-3T3 |
CARGO | Fluorophore (FITC) |
PMID | 21319732 |
PATENT | US20110027300 |
LENGTH | 14 |
Secondary Structure | CCSSCCCCCSSCCC |
SMILES | N[C@@H](CCCC[NH3])C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])CO |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |