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This page gives details of CPPsite entry with ID 1130
Primary information
CPPsite ID1130
PEPTIDE SEQUENCERQIKIWFQNRRMKWKA
PEPTIDE NAMEAla58 substitution mutant of pAntp (43-58)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYProbably Amphipathic
SUB CELLULAR LOCALIZATIONProbably Cytosol and nucleus, nucleoi
N-TERMINAL MODIFICATIONBiotinylation (Labeled with Biotinyl-beta-Alanine)
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYLow (20% relative to (pAntp) (43-58))
PROPOSED UPTAKE MECHANISMNon-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHaCat/ A549 cells
CARGOBiotin
PMID10784032
PATENTUS 7153931
LENGTH16
Secondary StructureCCCSSCCCCCCBTTBC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C=O
Tertiary Structure
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