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This page gives details of CPPsite entry with ID 1123 |
| Primary information | |
|---|---|
| CPPsite ID | 1123 |
| PEPTIDE SEQUENCE | RQIKIWFQARRMKWKK |
| PEPTIDE NAME | Ala51 substitution mutant of pAntp (43-58) |
| CHIRALITY | L |
| LINEAR/CYCLIC | Linear |
| SOURCE | Protein derived |
| CATEGORY | Probably Amphipathic |
| SUB CELLULAR LOCALIZATION | Probably Cytosol and nucleus, nucleoi |
| N-TERMINAL MODIFICATION | Biotinylation (Labeled with Biotinyl-beta-Alanine) |
| C-TERMINAL MODIFICATION | Amidation |
| UPTAKE EFFICIENCY | Medium (60% relative to (pAntp) (43-58)) |
| PROPOSED UPTAKE MECHANISM | Non-endocytic pathway |
| INVITRO/INVIVO | In vitro |
| CELL LINE | HaCat/ A549 cells |
| CARGO | Biotin |
| PMID | 10784032 |
| PATENT | US 7153931 |
| LENGTH | 16 |
| Secondary Structure | CCCCCHHHHHSCSSCC |
| SMILES | N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C=O |
| Tertiary Structure (Technique) | View in Jmol OR Download Structure (PEPstrMOD) |