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This page gives details of CPPsite entry with ID 1078
Primary information
CPPsite ID1078
PEPTIDE SEQUENCEKLGLKLGLKGLKGGLKLG
PEPTIDE NAMEVI
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYLow relative to I (pmol internalized peptide/mg pr
PROPOSED UPTAKE MECHANISMNon-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEAortic endothelial cells
CARGOFluorophore (fluorescein)
PMID10323198
PATENTUnknown
LENGTH18
Secondary StructureCCSTTCSSCCCCSSSTTC
SMILESN[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)NCC(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)NCC=O
Tertiary Structure
(Technique)
View in Jmol  OR Download Structure
 (PEPstrMOD)