This page gives details of CPPsite entry with ID 1067 |
Primary information | |
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CPPsite ID | 1067 |
PEPTIDE SEQUENCE | KALAKALAKLWKALAKAA |
PEPTIDE NAME | KLA12 |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
CATEGORY | Amphipathic |
SUB CELLULAR LOCALIZATION | Probably cytoplasm and nucleus |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Amidation |
UPTAKE EFFICIENCY | Medium relative to I (pmol internalized peptide/mg |
PROPOSED UPTAKE MECHANISM | Non-endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | Aortic endothelial cells |
PMID | 10323198 |
PATENT | Unknown |
LENGTH | 18 |
Secondary Structure | CTHHHHTTTTHHHHTTCC |
SMILES | N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |