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This page gives details of CPPsite entry with ID 1044
Primary information
CPPsite ID1044
PEPTIDE SEQUENCEGWTLNSAGYLLGKINLKALAALAKKIL
PEPTIDE NAMETransportan (TP)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEChimeric
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus and intracellular membranous structures
N-TERMINAL MODIFICATIONBiotinylation
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigh
PROPOSED UPTAKE MECHANISMNon-receptor mediated endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHuman bowes melanoma cells
CARGOBiotin
PMID10930519
PATENTUnknown
LENGTH27
Secondary StructureCCSHHHHTTTTTTTHHHHHHHHHHHHC
SMILESNCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C=O)CC(C)C)[C@H](CC)C)CCCC[NH3])CCCC[NH3])C)CC(C)C)C)C)CC(C)C)C)CCCC[NH3])CC(C)C)CC(=O)N)[C@H](CC)C)CCCC[NH3])CC(C)C)CC(C)C)Cc1ccc(cc1)O)C)CO)CC(=O)N)CC(C)C)[C@H](O)C)Cc1c[nH]c2c1cccc2
Tertiary Structure
(Technique)
View in Jmol  OR Download Structure
 (Experimentally determined structure from PDB)