This page gives details of CPPsite entry with ID 1039 |
Primary information | |
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CPPsite ID | 1039 |
PEPTIDE SEQUENCE | rrrrr |
PEPTIDE NAME | D-R5 |
CHIRALITY | D |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Probably cytoplasm and nucleus |
N-TERMINAL MODIFICATION | Conjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | Low (relative to Tat (49-57)) |
PROPOSED UPTAKE MECHANISM | Probably non-endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | Jurkat |
CARGO | Fluorophore (fluorescein) |
PMID | 11087855 |
PATENT | US 6593292 |
LENGTH | 5 |
Secondary Structure | CCCCC |
SMILES | N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |