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This page gives details of CPPsite entry with ID 1029
Primary information
CPPsite ID1029
PEPTIDE SEQUENCETRQARRNRRRRWRERQR
PEPTIDE NAMERev (34-50)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with fluorescein by C-terminal Cys amide
UPTAKE EFFICIENCYHigh (comparable to Tat (48-60)
PROPOSED UPTAKE MECHANISMNon-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINERAW 264.7
CARGOFluorophore (fluorescein)
PMID11084031
PATENTUS 20060223752
LENGTH17
Secondary StructureCTTTTTTHHHHHHHTC
SMILESN[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C)CCCNC(=[NH2])N)CCC(=O)N)CCCNC(=[NH2])N)CCC(=O)O)CCCNC(=[NH2])N)Cc1c[nH]c2c1cccc2)CCCNC(=[NH2])N)CCCNC(=[NH2])N)CCCNC(=[NH2])N)CCCNC(=[NH2])N)CC(=O)N)CCCNC(=[NH2])N)CCCNC(=[NH2])N)C)CCC(=O)N)CCCNC(=[NH2])N)[C@H](O)C
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (Experimentally determined structure from PDB)