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This page gives details of CPPsite entry with ID 1011
Primary information
CPPsite ID1011
PEPTIDE SEQUENCErkkrrqrrr
PEPTIDE NAMED-Tat (49-57)
CHIRALITYD
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONProbably cytoplasm and nucleus, nucleolus
N-TERMINAL MODIFICATIONConjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigh (greater than Tat (49-57))
PROPOSED UPTAKE MECHANISMProbably non-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEJurkat
CARGOFluorophore (fluorescein)
PMID11087855
PATENTUS 6593292
LENGTH9
Secondary StructureCGGGSSSCC
SMILESN[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCC[NH3])C(=O)N[C@H](CCCC[NH3])C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCC(=O)N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)