This page gives details of CPPsite entry with ID 1006 |
Primary information | |
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CPPsite ID | 1006 |
PEPTIDE SEQUENCE | RKKRRQRRR |
PEPTIDE NAME | Tat (49-57) |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Probably cytoplasm and nucleus, nucleolus |
N-TERMINAL MODIFICATION | Conjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | High |
PROPOSED UPTAKE MECHANISM | Probably non-endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | Jurkat |
CARGO | Fluorophore (fluorescein) |
PMID | 11087855 |
PATENT | US 6593292 |
LENGTH | 9 |
Secondary Structure | CCCCCSCCC |
SMILES | N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |