This tool has been developed to predict cell-penetrating peptides (CPPs) and their subcellular localization. Users may paste or upload a file containing one or more peptide sequences in FASTA format. Each sequence will be evaluated using a ExtraTree (ET) classifier built on AAC feature for stage I classification to determine whether it is a CPP, and if so, then the precited CPPs will move futher for stage II localization prediction using CatBoost model built on DDR feature to identify their predicted intracellular destination — Cytoplasm, Mitochondria, Nucleus, Endo_lysosome, and Others. The threshold can be adjusted to control prediction sensitivity. For detailed information on input format and interpretation of results, please visit the Help page.