Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_1216
Primary information
B3PDB IDb3pdb_1216
Peptide NameP20
PEPTIDE SEQUENCE (1-letter)VQIYK
PEPTIDE SEQUENCE (3-letter)NA
N-terminal modificationNA
C-terminal modificationC-terminal amidation
Chemical modificationNA
Peptide Length6
ConformationLinear
Peptide NatureNA
Source/Origin of peptideChemically synthesized
SMILESNA
Cell LineHuman brain endothelial cells (EA.hy926)
In vitro CONCENTRATIONNA
In vitro METHODField-emission transmission electron microscope
In vitro RESULTA3 peptide treated with this peptide, showed higher folds of decrease in fluorescence intensities a
ANIMAL MODELNA
In vivo CONCENTRATIONNA
In vivo MODE OF DELIVERYNA
In vivo METHODNA
In vivo RESULTNA
ACTIONTrojan peptides are capable of translo- cating the BBB, without affecting its interity.
TRANSPORT TYPETranslocation
SUBCELLULAR LOCALISATIONNA
COMBINATIONComined with A3 pepide
PHYSICAL CONDITIONTauopathies
RESPONSEThese peptides were capable of reducing the tau elicit toxicity by accelerating or impeding the self
RESULTThese peptide-based modulators (Trojans) were non-amyloidogenic, stable in serum and showed minimal
LABELNA
PMID32114026