Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_1209
Primary information
B3PDB IDb3pdb_1209
Peptide NamePenetratin
PEPTIDE SEQUENCE (1-letter)RQIKIWFQNRRMKWKK
PEPTIDE SEQUENCE (3-letter)NA
N-terminal modificationNA
C-terminal modificationNA
Chemical modificationNA
Peptide Length16
ConformationLinear
Peptide NatureNA
Source/Origin of peptideChemically synthesized
SMILESNA
Cell LineNA
In vitro CONCENTRATIONNA
In vitro METHODNA
In vitro RESULTNA
ANIMAL MODELMale Sprague-Dawley rats
In vivo CONCENTRATION2.0 mM
In vivo MODE OF DELIVERYIntranasal
In vivo METHODELISA
In vivo RESULTL-penetratin increased the systemic absorption of leptin after intranasal administration.
ACTIONThe intranasal coadministration with L-penetratin could deliver leptin to the brain and in particula
TRANSPORT TYPEPermeability
SUBCELLULAR LOCALISATIONHypothalamus
COMBINATIONCombined with leptin
PHYSICAL CONDITIONObesity
RESPONSENA
RESULTThe intranasal coadministration with L-penetratin has a potential to deliver leptin into the therape
LABELNA
PMID31926192