Detailed description page of B3Pdb
This page provides detail information of Selected ID b3pdb_1208 |
| Primary information | |
|---|---|
| B3PDB ID | b3pdb_1208 |
| Peptide Name | Adiponetic peptide |
| PEPTIDE SEQUENCE (1-letter) | LQVYGDGDHNGLYADNVN |
| PEPTIDE SEQUENCE (3-letter) | NA |
| N-terminal modification | NA |
| C-terminal modification | NA |
| Chemical modification | NA |
| Peptide Length | 18 |
| Conformation | Linear |
| Peptide Nature | NA |
| Source/Origin of peptide | NA |
| SMILES | NA |
| Cell Line | NA |
| In vitro CONCENTRATION | NA |
| In vitro METHOD | NA |
| In vitro RESULT | NA |
| ANIMAL MODEL | C57BL/6J mice |
| In vivo CONCENTRATION | 15 mg/kg of APNp |
| In vivo MODE OF DELIVERY | Intraperitoneal |
| In vivo METHOD | Fourier Transform Infrared Spectroscopy |
| In vivo RESULT | APNp suppressed mitochondrial and ATF4-CHOP apoptosis pathways in a Smad3 dependent manner. |
| ACTION | NA |
| TRANSPORT TYPE | Permeability |
| SUBCELLULAR LOCALISATION | NA |
| COMBINATION | Alone |
| PHYSICAL CONDITION | ICH injury in diabetic mice |
| RESPONSE | NA |
| RESULT | APNp promoted neural sur- vival following ICH injury in the diabetic setting, by suppressing mitocho |
| LABEL | NA |
| PMID | 31922310 |