Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_0447
Primary information
B3PDB IDb3pdb_0447
Peptide NameNeuropeptide Y
PEPTIDE SEQUENCE (1-letter)YPSKPDNPGEDAPAEDLARYYSALRHYINLITRQRY
PEPTIDE SEQUENCE (3-letter)Tyr-Pro- Ser-Lys -Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala - Pro-Ala -Glu-Asp-Leu-AIa-Arg-Tyr -Tyr- Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr
N-terminal modificationNA
C-terminal modificationNA
Chemical modificationNA
Peptide Length36
ConformationLinear
Peptide NatureNA
Source/Origin of peptidebovine,porcine
SMILESCCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CC3=CN=CN3)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C6CCCN6C(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C7CCCN7C(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C8CCCN8C(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C9CCCN9C(=O)C(CC1=CC=C(C=C1)O)N
Cell LineNA
In vitro CONCENTRATIONNA
In vitro METHODEfflux study ICU
In vitro RESULTNA
ANIMAL MODELNA
In vivo CONCENTRATIONNA
In vivo MODE OF DELIVERYNA
In vivo METHODNA
In vivo RESULTNA
ACTIONNA
TRANSPORT TYPEPermeability
SUBCELLULAR LOCALISATIONNA
COMBINATIONNA
PHYSICAL CONDITIONNA
RESPONSEBrain elemination rate constant
RESULT0.03 min-1
LABELDirect iodination
PMID10070013