Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_0232
Primary information
B3PDB IDb3pdb_0232
Peptide NameNA
PEPTIDE SEQUENCE (1-letter)RGD
PEPTIDE SEQUENCE (3-letter)ArgGlyAsp
N-terminal modificationNA
C-terminal modificationNA
Chemical modificationNA
Peptide Length3
ConformationLinear
Peptide NatureCationic
Source/Origin of peptideChemically synthesized
SMILESNA
Cell LineNA
In vitro CONCENTRATIONNA
In vitro METHODNA
In vitro RESULTNA
ANIMAL MODELBALB/c mice xenograft for U87MG glioma cells
In vivo CONCENTRATION5mg/Kg
In vivo MODE OF DELIVERYIntravenous
In vivo METHODFluoroscent measurement
In vivo RESULTSignificant amount of drugsa delivered in brain tissue
ACTIONPeptide can deliver drugs into brain tissue
TRANSPORT TYPENA
SUBCELLULAR LOCALISATIONNA
COMBINATIONDoxorubicin+paclitaxel in 5mg/Kg combination
PHYSICAL CONDITIONBrain glioma therapy
RESPONSENA
RESULTNA
LABELNA
PMID27143884