Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_0150
Primary information
B3PDB IDb3pdb_0150
Peptide NameMMP-2200
PEPTIDE SEQUENCE (1-letter)Y-D-TGFLS(β-O-Glc)-CONH2
PEPTIDE SEQUENCE (3-letter)Tyr-D-Thr-Gly-Phe-Leu-Ser(β-O-Glc)-CONH2
N-terminal modificationNA
C-terminal modificationNA
Chemical modificationGlycosylated serine residue
Peptide Length6
ConformationLinear
Peptide NatureNA
Source/Origin of peptideChemically synthesized
SMILESNA
Cell LineNA
In vitro CONCENTRATIONNA
In vitro METHODNA
In vitro RESULTNA
ANIMAL MODELAdult Sprague-Dawley rats
In vivo CONCENTRATION10mg/Kg
In vivo MODE OF DELIVERYIntraperitoneal
In vivo METHODMicrodialysis analysis and LCMS analysis
In vivo RESULTSignificant amount of peptide crosses blood brain barrier after 12 minute and remain stable up to 80
ACTIONShows potent analgesic behaviour
TRANSPORT TYPENA
SUBCELLULAR LOCALISATIONNA
COMBINATIONNA
PHYSICAL CONDITIONParkinson
RESPONSEStability/half life
RESULT80 minute
LABELNA
PMID23127847