Detailed description page of B3Pdb
This page provides detail information of Selected ID b3pdb_0148 |
| Primary information | |
|---|---|
| B3PDB ID | b3pdb_0148 |
| Peptide Name | PACAP-TAT peptide |
| PEPTIDE SEQUENCE (1-letter) | PACAP-YGRKKRRQRRR |
| PEPTIDE SEQUENCE (3-letter) | PACAP-TyrGlyArgLysLysArgArgGlnArgArgArg |
| N-terminal modification | NA |
| C-terminal modification | Conjugated with TAT |
| Chemical modification | NA |
| Peptide Length | NA |
| Conformation | Cyclic |
| Peptide Nature | Cationic |
| Source/Origin of peptide | Natural from pituitary gland |
| SMILES | NA |
| Cell Line | NA |
| In vitro CONCENTRATION | NA |
| In vitro METHOD | NA |
| In vitro RESULT | NA |
| ANIMAL MODEL | Male NIH mouse |
| In vivo CONCENTRATION | 100 nmol/Kg |
| In vivo MODE OF DELIVERY | Intraperitoneal |
| In vivo METHOD | Fluoroscent screening by FITC labbled peptide maass in brain tissue |
| In vivo RESULT | crosses blood brain barrier with 6.55+/-0.55% efficacy |
| ACTION | NA |
| TRANSPORT TYPE | NA |
| SUBCELLULAR LOCALISATION | NA |
| COMBINATION | NA |
| PHYSICAL CONDITION | Alzheimer |
| RESPONSE | NA |
| RESULT | NA |
| LABEL | NA |
| PMID | 22939769 |