Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_0147
Primary information
B3PDB IDb3pdb_0147
Peptide NameGoldnanoparticle con
PEPTIDE SEQUENCE (1-letter)THRPPMWSPVWP
PEPTIDE SEQUENCE (3-letter)ThrHisArgProProMetTrpSerProValTrpPro
N-terminal modificationNA
C-terminal modificationNA
Chemical modificationConjugated with CLPFFD goldnaNAparticle
Peptide Length12
ConformationLinear
Peptide NatureCationic
Source/Origin of peptideChemically synthesized
SMILESNA
Cell LineNA
In vitro CONCENTRATIONNA
In vitro METHODNA
In vitro RESULTNA
ANIMAL MODELAdult Sprague-Dawley rats
In vivo CONCENTRATION1.86 mg/Kg
In vivo MODE OF DELIVERYIntraperitoneal
In vivo METHODInstrumental neutron activation analysis and Nissl staining
In vivo RESULTConjugate was found to cross blodd brain barrier; does not effect mice survival; no toxicity as meas
ACTIONNA
TRANSPORT TYPENA
SUBCELLULAR LOCALISATIONNA
COMBINATIONNA
PHYSICAL CONDITIONAlzheimer
RESPONSENA
RESULTNA
LABELNA
PMID22795856