Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_0072
Primary information
B3PDB IDb3pdb_0072
Peptide NameNeurotensin
PEPTIDE SEQUENCE (1-letter)ELYENKPRRPYIL
PEPTIDE SEQUENCE (3-letter)pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH
N-terminal modificationNA
C-terminal modificationNA
Chemical modificationNA
Peptide Length13
ConformationTridecapeptide
Peptide NatureNA
Source/Origin of peptidebovine hypothalamus
SMILESN[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)O
Cell LineNA
In vitro CONCENTRATIONNA
In vitro METHODNA
In vitro RESULTNA
ANIMAL MODELAdult male Swiss-Webster mice
In vivo CONCENTRATIONNA
In vivo MODE OF DELIVERYNA
In vivo METHODStudent's t-test (two-tailed) and Mann-Whitney U-test
In vivo RESULTNA
ACTIONNot able to cross the BBB in sufficient quantities to exert direct brain effects. Can modify the sed
TRANSPORT TYPENA
SUBCELLULAR LOCALISATIONNA
COMBINATIONNA
PHYSICAL CONDITIONNA
RESPONSENA
RESULTNA
LABELNA
PMID406965