Detailed description page of B3Pdb
This page provides detail information of Selected ID b3pdb_0061 |
| Primary information | |
|---|---|
| B3PDB ID | b3pdb_0061 |
| Peptide Name | PPII(L3X;L15X) |
| PEPTIDE SEQUENCE (1-letter) | VRXPPPVRLPPPVRXPPP |
| PEPTIDE SEQUENCE (3-letter) | ValArgXaaProProProValArgLeuProProProValArgXaaProProPro |
| N-terminal modification | CuAAC conjugated at N-terminus |
| C-terminal modification | NA |
| Chemical modification | NA |
| Peptide Length | 18 |
| Conformation | Linear |
| Peptide Nature | NA |
| Source/Origin of peptide | Chemically synthesized |
| SMILES | N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)O |
| Cell Line | bEnd.3 cells |
| In vitro CONCENTRATION | NA |
| In vitro METHOD | Immunofluorescence microscopy |
| In vitro RESULT | It shows the permeability towards the BBB. |
| ANIMAL MODEL | NA |
| In vivo CONCENTRATION | NA |
| In vivo MODE OF DELIVERY | NA |
| In vivo METHOD | NA |
| In vivo RESULT | NA |
| ACTION | These novel peptide conjugates have the capacity to act as promising brain shuttles |
| TRANSPORT TYPE | Receptor-mediated transcytosis |
| SUBCELLULAR LOCALISATION | NA |
| COMBINATION | Combined |
| PHYSICAL CONDITION | NA |
| RESPONSE | NA |
| RESULT | NA |
| LABEL | NA |
| PMID | 32055384 |