Detailed description page of B3Pdb
This page provides detail information of Selected ID b3pdb_0057 |
Primary information | |
---|---|
B3PDB ID | b3pdb_0057 |
Peptide Name | PPII(R8X) |
PEPTIDE SEQUENCE (1-letter) | VRLPPPVXLPPPVRLPPP |
PEPTIDE SEQUENCE (3-letter) | ValArgLeuProProProValXaaLeuProProProValArgLeuProProPro |
N-terminal modification | CuAAC conjugated at N-terminus |
C-terminal modification | NA |
Chemical modification | NA |
Peptide Length | 18 |
Conformation | Linear |
Peptide Nature | NA |
Source/Origin of peptide | Chemically synthesized |
SMILES | N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)O |
Cell Line | bEnd.3 cells |
In vitro CONCENTRATION | NA |
In vitro METHOD | Immunofluorescence microscopy |
In vitro RESULT | It shows the permeability towards the BBB. |
ANIMAL MODEL | NA |
In vivo CONCENTRATION | NA |
In vivo MODE OF DELIVERY | NA |
In vivo METHOD | NA |
In vivo RESULT | NA |
ACTION | These novel peptide conjugates have the capacity to act as promising brain shuttles |
TRANSPORT TYPE | Receptor-mediated transcytosis |
SUBCELLULAR LOCALISATION | NA |
COMBINATION | Combined |
PHYSICAL CONDITION | NA |
RESPONSE | NA |
RESULT | NA |
LABEL | NA |
PMID | 32055384 |